Anti-AP4M1 antibody (312-362 aa) (STJ198137)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human AP4M1 at the amino acid range 312-362
General Information
| Short Description | Rabbit polyclonal anti-AP-4 complex subunit mu-1 (312-362 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AP4M1 |
| Gene ID | 9179 |
| Uniprot ID | AP4M1_HUMAN |
| Immunogen | Synthesized peptide derived from the human AP4M1 at the amino acid range 312-362 |
| Immunogen Region | 312-362 aa |
| Specificity | This antibody detects endogenous levels of human AP4M1 |
Additional Info
| Function | Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos. The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal. |
| Protein Name | Ap-4 Complex Subunit Mu-1Ap-4 Adaptor Complex Mu SubunitAdaptor-Related Protein Complex 4 Subunit Mu-1Mu Subunit Of Ap-4Mu-Adaptin-Related Protein 2Mu-Arp2Mu4-AdaptinMu4 |
| Database Links | Reactome: R-HSA-432720 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembranePeripheral Membrane ProteinEarly EndosomeFound In Soma And Dendritic Shafts Of Neuronal Cells |
| Alternative Antibody Names | Anti-Ap-4 Complex Subunit Mu-1 antibodyAnti-Ap-4 Adaptor Complex Mu Subunit antibodyAnti-Adaptor-Related Protein Complex 4 Subunit Mu-1 antibodyAnti-Mu Subunit Of Ap-4 antibodyAnti-Mu-Adaptin-Related Protein 2 antibodyAnti-Mu-Arp2 antibodyAnti-Mu4-Adaptin antibodyAnti-Mu4 antibodyAnti-AP4M1 antibodyAnti-MUARP2 antibody |
Information sourced from Uniprot.org