| Function | Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos. The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal. |
| Protein Name | Ap-4 Complex Subunit Mu-1Ap-4 Adaptor Complex Mu SubunitAdaptor-Related Protein Complex 4 Subunit Mu-1Mu Subunit Of Ap-4Mu-Adaptin-Related Protein 2Mu-Arp2Mu4-AdaptinMu4 |
| Database Links | Reactome: R-HSA-432720 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembranePeripheral Membrane ProteinEarly EndosomeFound In Soma And Dendritic Shafts Of Neuronal Cells |
| Alternative Antibody Names | Anti-Ap-4 Complex Subunit Mu-1 antibodyAnti-Ap-4 Adaptor Complex Mu Subunit antibodyAnti-Adaptor-Related Protein Complex 4 Subunit Mu-1 antibodyAnti-Mu Subunit Of Ap-4 antibodyAnti-Mu-Adaptin-Related Protein 2 antibodyAnti-Mu-Arp2 antibodyAnti-Mu4-Adaptin antibodyAnti-Mu4 antibodyAnti-AP4M1 antibodyAnti-MUARP2 antibody |
Information sourced from Uniprot.org
