| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ANP32E (1-70) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ANP32E |
| Gene ID: |
81611 |
| Uniprot ID: |
AN32E_HUMAN |
| Immunogen Region: |
1-70 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human ANP32E (NP_112182.1). |
| Immunogen Sequence: |
MEMKKKINLELRNRSPEEVT ELVLDNCLCVNGEIEGLNDT FKELEFLSMANVELSSLARL PSLNKLRKLE |
| Tissue Specificity | Expressed in peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney. |
| Post Translational Modifications | Phosphorylated. The phosphorylation is nuclear localization signal (NLS)-dependent. |
| Function | Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis. |
| Protein Name | Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member ELanp-Like ProteinLanp-L |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member E antibodyAnti-Lanp-Like Protein antibodyAnti-Lanp-L antibodyAnti-ANP32E antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
