Anti-ANP32E antibody (1-70) (STJ11102885)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ANP32E (1-70) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ANP32E |
| Gene ID | 81611 |
| Uniprot ID | AN32E_HUMAN |
| Immunogen Region | 1-70 |
| Immunogen Sequence | MEMKKKINLELRNRSPEEVT ELVLDNCLCVNGEIEGLNDT FKELEFLSMANVELSSLARL PSLNKLRKLE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human ANP32E (NP_112182.1). |
Additional Info
| Tissue Specificity | Expressed in peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney. |
| Post Translational Modifications | Phosphorylated. The phosphorylation is nuclear localization signal (NLS)-dependent. |
| Function | Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis. |
| Protein Name | Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member ELanp-Like ProteinLanp-L |
| Database Links | |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Acidic Leucine-Rich Nuclear Phosphoprotein 32 Family Member E antibodyAnti-Lanp-Like Protein antibodyAnti-Lanp-L antibodyAnti-ANP32E antibody |
Information sourced from Uniprot.org