| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Ankyrin repeat domain-containing protein 2 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ANKRD2 |
| Gene ID: |
26287 |
| Uniprot ID: |
ANKR2_HUMAN |
| Specificity: |
This antibody detects endogenous levels of ANKRD2 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human ANKRD2 |
| Post Translational Modifications | Phosphorylation at Ser-99 by PKB/AKT2 in response to oxidative stress induces translocation to the nucleus and negatively regulates myoblast differentiation. |
| Function | Functions as a negative regulator of myocyte differentiation. May interact with both sarcoplasmic structural proteins and nuclear proteins to regulate gene expression during muscle development and in response to muscle stress. |
| Protein Name | Ankyrin Repeat Domain-Containing Protein 2Skeletal Muscle Ankyrin Repeat ProteinHarpp |
| Cellular Localisation | CytoplasmMyofibrilSarcomereI BandCytosolNucleusPml BodyIn The Sarcoplasm Of Differentiated Striated Muscle CellsWhere It Is Cytosolic And Enriched In The I BandIn Nucleus And Pml Bodies Of Proliferating And Undifferentiated MyoblastsAssociates With The Euchromatin In The Nucleus Of Myocytes Upon Muscle Stress |
| Alternative Antibody Names | Anti-Ankyrin Repeat Domain-Containing Protein 2 antibodyAnti-Skeletal Muscle Ankyrin Repeat Protein antibodyAnti-Harpp antibodyAnti-ANKRD2 antibodyAnti-ARPP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
