| Function | Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit. Coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly. May regulate nuclear localization of VRK1 in non-dividing cells. It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex. Involved in brain development. |
| Protein Name | Ankyrin Repeat And Lem Domain-Containing Protein 2Lem Domain-Containing Protein 4 |
| Database Links | Reactome: R-HSA-2995383Reactome: R-HSA-9013404Reactome: R-HSA-9013408 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Iii Membrane Protein |
| Alternative Antibody Names | Anti-Ankyrin Repeat And Lem Domain-Containing Protein 2 antibodyAnti-Lem Domain-Containing Protein 4 antibodyAnti-ANKLE2 antibodyAnti-KIAA0692 antibodyAnti-LEM4 antibody |
Information sourced from Uniprot.org
