Anti-ANAPC10 antibody (1-185) (STJ110628)

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STJ110628
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Short Description :Rabbit polyclonal ANAPC10 (1-185) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:ANAPC10
Gene ID:10393
Uniprot ID:APC10_HUMAN
Immunogen Region:1-185
Immunogen Sequence:MTTPNKTPPGADPKQLERTG TVREIGSQAVWSLSSCKPGF GVDQLRDDNLETYWQSDGSQ PHLVNIQFRRKTTVKTLCIY ADYKSDESYTPSKISVRVGN NFHNLQEIRQLELVEPSGWI HVPLTDNHKKPTRTFMIQIA VLANHQNGRDTHMRQIKIYT PVEESSIGKFPRCTTIDFMM YRSIR
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human ANAPC10 (NP_055700.2).
Function Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins.
Protein Name Anaphase-Promoting Complex Subunit 10
Apc10
Cyclosome Subunit 10
Database Links Reactome: R-HSA-141430
Reactome: R-HSA-174048
Reactome: R-HSA-174084
Reactome: R-HSA-174154
Reactome: R-HSA-174178
Reactome: R-HSA-174184
Reactome: R-HSA-176407
Reactome: R-HSA-176408
Reactome: R-HSA-176409
Reactome: R-HSA-176412
Reactome: R-HSA-179409
Reactome: R-HSA-2467813
Reactome: R-HSA-2559582
Reactome: R-HSA-68867
Reactome: R-HSA-69017
Reactome: R-HSA-8853884
Reactome: R-HSA-9687136
Reactome: R-HSA-983168
Cellular Localisation
Alternative Antibody Names Anti-Anaphase-Promoting Complex Subunit 10 antibody
Anti-Apc10 antibody
Anti-Cyclosome Subunit 10 antibody
Anti-ANAPC10 antibody
Anti-APC10 antibody

Information sourced from Uniprot.org