• Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-AMOTL2 antibody (201-251 aa) (STJ194903)

SKU:
STJ194903

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Angiomotin-like protein 2 (201-251 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AMOTL2
Gene ID: 51421
Uniprot ID: AMOL2_HUMAN
Immunogen Region: 201-251 aa
Specificity: This antibody detects endogenous levels of AMOL2 at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human AMOL2 at the amino acid range 201-251
Function Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC.
Protein Name Angiomotin-Like Protein 2
Leman Coiled-Coil Protein
Lccp
Database Links Reactome: R-HSA-2028269
Cellular Localisation Recycling Endosome
Alternative Antibody Names Anti-Angiomotin-Like Protein 2 antibody
Anti-Leman Coiled-Coil Protein antibody
Anti-Lccp antibody
Anti-AMOTL2 antibody
Anti-KIAA0989 antibody

Information sourced from Uniprot.org

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