| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Angiomotin-like protein 2 (201-251 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AMOTL2 |
| Gene ID: |
51421 |
| Uniprot ID: |
AMOL2_HUMAN |
| Immunogen Region: |
201-251 aa |
| Specificity: |
This antibody detects endogenous levels of AMOL2 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human AMOL2 at the amino acid range 201-251 |
| Function | Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC. |
| Protein Name | Angiomotin-Like Protein 2Leman Coiled-Coil ProteinLccp |
| Database Links | Reactome: R-HSA-2028269 |
| Cellular Localisation | Recycling Endosome |
| Alternative Antibody Names | Anti-Angiomotin-Like Protein 2 antibodyAnti-Leman Coiled-Coil Protein antibodyAnti-Lccp antibodyAnti-AMOTL2 antibodyAnti-KIAA0989 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
