Anti-ALS2CL antibody (606-656 aa) (STJ193682)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human AL2CL at the amino acid range 606-656
General Information
| Short Description | Rabbit polyclonal anti-ALS2 C-terminal-like protein (606-656 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ALS2CL |
| Gene ID | 259173 |
| Uniprot ID | AL2CL_HUMAN |
| Immunogen | Synthesized peptide derived from the human AL2CL at the amino acid range 606-656 |
| Immunogen Region | 606-656 aa |
| Specificity | This antibody detects endogenous levels of AL2CL at Human/Mouse |
Additional Info
| Function | Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics. |
| Protein Name | Als2 C-Terminal-Like Protein |
| Database Links | Reactome: R-HSA-8876198 |
| Cellular Localisation | CytoplasmDistributed Onto The Vesicular Compartments In The Cytoplasm With Strong Punctated StainingColocalizes With Rab5a Onto The Vesicular/Membranous Compartments In The CytoplasmParticularly To The Leading Edges Of The Cells |
| Alternative Antibody Names | Anti-Als2 C-Terminal-Like Protein antibodyAnti-ALS2CL antibody |
Information sourced from Uniprot.org