| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ALS2 C-terminal-like protein (606-656 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ALS2CL |
| Gene ID: |
259173 |
| Uniprot ID: |
AL2CL_HUMAN |
| Immunogen Region: |
606-656 aa |
| Specificity: |
This antibody detects endogenous levels of AL2CL at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human AL2CL at the amino acid range 606-656 |
| Function | Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics. |
| Protein Name | Als2 C-Terminal-Like Protein |
| Database Links | Reactome: R-HSA-8876198 |
| Cellular Localisation | CytoplasmDistributed Onto The Vesicular Compartments In The Cytoplasm With Strong Punctated StainingColocalizes With Rab5a Onto The Vesicular/Membranous Compartments In The CytoplasmParticularly To The Leading Edges Of The Cells |
| Alternative Antibody Names | Anti-Als2 C-Terminal-Like Protein antibodyAnti-ALS2CL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
