Anti-alpha-1-antichymotrypsin antibody (222-236) (STJ73368)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-alpha-1-antichymotrypsin (222-236) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 65kDa band observed in Human Albumin-depleted Serum and Plasma lysates (calculated MW of 47.7kDa according to NP_001076.2). The observed molecular weight corresponds to the gly |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SERPINA3 |
| Gene ID | 12 |
| Uniprot ID | AACT_HUMAN |
| Accession Number | NP_001076.2 |
| Immunogen Region | 222-236 |
| Immunogen Sequence | DPQDTHQSRFYLSKK |
Additional Info
| Post Translational Modifications | N- and O-glycosylated. |
| Function | Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2. |
| Protein Name | Alpha-1-AntichymotrypsinActCell Growth-Inhibiting Gene 24/25 ProteinSerpin A3 Cleaved Into - Alpha-1-Antichymotrypsin His-Pro-Less |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Alpha-1-Antichymotrypsin antibodyAnti-Act antibodyAnti-Cell Growth-Inhibiting Gene 24/25 Protein antibodyAnti-Serpin A3 Cleaved Into - Alpha-1-Antichymotrypsin His-Pro-Less antibodyAnti-SERPINA3 antibodyAnti-AACT antibodyAnti-GIG24 antibodyAnti-GIG25 antibody |
Information sourced from Uniprot.org