• STJ73368 (0. 3µg/ml) staining of albumin-depleted Serum (A) and Plasma (B) lysates (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-alpha-1-antichymotrypsin antibody (222-236) (STJ73368)

SKU:
STJ73368-100

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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-alpha-1-antichymotrypsin (222-236) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.3-1µg/ml
ELISA-antibody detection limit dilution 1:128000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: SERPINA3
Gene ID: 12
Uniprot ID: AACT_HUMAN
Immunogen Region: 222-236
Accession Number: NP_001076.2
Immunogen Sequence: DPQDTHQSRFYLSKK
Post Translational Modifications N- and O-glycosylated.
Function Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.
Protein Name Alpha-1-Antichymotrypsin
Act
Cell Growth-Inhibiting Gene 24/25 Protein
Serpin A3 Cleaved Into - Alpha-1-Antichymotrypsin His-Pro-Less
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-6798695
Cellular Localisation Secreted
Alternative Antibody Names Anti-Alpha-1-Antichymotrypsin antibody
Anti-Act antibody
Anti-Cell Growth-Inhibiting Gene 24/25 Protein antibody
Anti-Serpin A3 Cleaved Into - Alpha-1-Antichymotrypsin His-Pro-Less antibody
Anti-SERPINA3 antibody
Anti-AACT antibody
Anti-GIG24 antibody
Anti-GIG25 antibody

Information sourced from Uniprot.org

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