Anti-ALB antibody (Full Length) (STJ140089)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
ImmunogenPurified full length native Albumin.
General Information
| Short Description | Goat polyclonal Albumin (Full Length) antibody for use in WB in human, mouse, rat, bovine, canine, chicken, avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep and simian samples. Datasheet included with dilution recommend |
| Applications | WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Bovine/Canine/Chicken/Avian/Donkey/Feline/Goat/Guinea Pig/Hamster/Horse/Porcine/Rabbit/Sheep/Simian |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 3 mg/mL |
| Purification | This antibody is epitope-affinity purified from goat antiserum. |
| Dilution Range | WB 1:500-1:5000 |
| Formulation | PBS, 20% Glycerol and 0.05% Sodium Azide. |
| Storage Instruction | For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours. |
Target Information
| Gene Symbol | ALB |
| Gene ID | 213 |
| Uniprot ID | ALBU_HUMAN |
| Accession Number | ENSG00000163631 |
| Immunogen | Purified full length native Albumin. |
| Immunogen Region | Full Length |
| Immunogen Sequence | MKWVTFISLLLLFSSAYSRG KWVTFISLLLLFSSAYSRGV WVTFISLLLLFSSAYSRGVF VTFISLLLLFSSAYSRGVFR TFISLLLLFSSAYSRGVFRR FISLLLLFSSAYSRGVFRRD ISLLLLFSSAYSRGVFRRDT SLLLLFSSAYSRGVFRRDTH LLLLFSSAYSRGVFRRDTHK LLLFSSAYSRGVFRRDTHKS LLFSSAYSRGVFRRDTHKSE LFSSAYSRGVFRRDTHKSE |
| Specificity | Using serum samples detects a band around 66 kDa by Western blot. |
Additional Info
| Tissue Specificity | Plasma. |
| Post Translational Modifications | Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606. Glycated in diabetic patients. Phosphorylated by FAM20C in the extracellular medium. Acetylated on Lys-223 by acetylsalicylic acid. |
| Function | Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma. Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood. The rank order of affinity is zinc > calcium > magnesium. Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli. Does not prevent iron uptake by the bacterial siderophore aerobactin. |
| Protein Name | Albumin |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-159418Reactome: R-HSA-189451Reactome: R-HSA-189483Reactome: R-HSA-2168880Reactome: R-HSA-381426Reactome: R-HSA-8957275Reactome: R-HSA-8964058Reactome: R-HSA-9707564Reactome: R-HSA-9749641Reactome: R-HSA-9757110Reactome: R-HSA-9793528 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Albumin antibodyAnti-ALB antibodyAnti-GIG20 antibodyAnti-GIG42 antibodyAnti-PRO0903 antibodyAnti-PRO1708 antibodyAnti-PRO2044 antibodyAnti-PRO2619 antibodyAnti-PRO2675 antibodyAnti-UNQ696 antibodyAnti-PRO1341 antibody |
Information sourced from Uniprot.org