Anti-AKT antibody [3B11-G8-B1] (STJA0033186)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant human AKT1 protein fragments expressed in E.coli.AKT1 interacts (via the C-terminus) with CCDC88A (via its C-terminus). Interacts with GRB10; the interaction leads to GRB10 phosphorylation thus promoting YWHAE-binding By similari
General Information
| Short Description | Mouse monoclonal anti-AKT for use in WB and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 3B11-G8-B1 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IP 1:20 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | AKT3AKT210000208207AKT3_HUMANAKT2_HUMANAKT1_HUMAN |
| Immunogen | Purified recombinant human AKT1 protein fragments expressed in E.coli.AKT1 interacts (via the C-terminus) with CCDC88A (via its C-terminus). Interacts with GRB10; the interaction leads to GRB10 phosphorylation thus promoting YWHAE-binding By similari |
Additional Info
| Tissue Specificity | Q9Y243 - In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney.P31751 - Widely expressed. Expressed in myoblasts.P31749 - Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages.Q9Y243 - In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney.P31751 - Widely expressed. Expressed in myoblasts.P31749 - Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages. |
| Alternative Antibody Names | Anti-Rac-Gamma Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase Akt-3 antibodyAnti-Protein Kinase B Gamma antibodyAnti-Pkb Gamma antibodyAnti-Rac-Pk-Gamma antibodyAnti-Stk-2 antibodyAnti-AKT3 antibodyAnti-PKBG antibodyAnti-Rac-Beta Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase Akt-2 antibodyAnti-Protein Kinase B Beta antibodyAnti-Pkb Beta antibodyAnti-Rac Protein Kinase Beta antibodyAnti-Rac-Pk-Beta antibodyAnti-AKT2 antibodyAnti-Rac-Alpha Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase B antibodyAnti-Pkb antibodyAnti-Protein Kinase B Alpha antibodyAnti-Pkb Alpha antibodyAnti-Proto-Oncogene C-Akt antibodyAnti-Rac-Pk-Alpha antibodyAnti-AKT1 antibodyAnti-PKB antibodyAnti-RAC antibodyAnti-Rac-Gamma Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase Akt-3 antibodyAnti-Protein Kinase B Gamma antibodyAnti-Pkb Gamma antibodyAnti-Rac-Pk-Gamma antibodyAnti-Stk-2 antibodyAnti-AKT3 antibodyAnti-PKBG antibodyAnti-Rac-Beta Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase Akt-2 antibodyAnti-Protein Kinase B Beta antibodyAnti-Pkb Beta antibodyAnti-Rac Protein Kinase Beta antibodyAnti-Rac-Pk-Beta antibodyAnti-AKT2 antibodyAnti-Rac-Alpha Serine/Threonine-Protein Kinase antibodyAnti-Protein Kinase B antibodyAnti-Pkb antibodyAnti-Protein Kinase B Alpha antibodyAnti-Pkb Alpha antibodyAnti-Proto-Oncogene C-Akt antibodyAnti-Rac-Pk-Alpha antibodyAnti-AKT1 antibodyAnti-PKB antibodyAnti-RAC antibody |
Information sourced from Uniprot.org