| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Aflatoxin B1 aldehyde reductase member 2 (219-269) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AKR7A2 |
| Gene ID: |
8574 |
| Uniprot ID: |
ARK72_HUMAN |
| Immunogen Region: |
219-269 |
| Specificity: |
This antibody detects endogenous levels of human ARK72 |
| Immunogen: |
Synthesized peptide derived from human ARK72 AA range: 219-269 |
| Function | Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. |
| Protein Name | Aflatoxin B1 Aldehyde Reductase Member 2Afb1 Aldehyde Reductase 1Afb1-Ar 1Aldoketoreductase 7Succinic Semialdehyde ReductaseSsa Reductase |
| Database Links | Reactome: R-HSA-5423646 |
| Cellular Localisation | MitochondrionGolgi ApparatusCytoplasm |
| Alternative Antibody Names | Anti-Aflatoxin B1 Aldehyde Reductase Member 2 antibodyAnti-Afb1 Aldehyde Reductase 1 antibodyAnti-Afb1-Ar 1 antibodyAnti-Aldoketoreductase 7 antibodyAnti-Succinic Semialdehyde Reductase antibodyAnti-Ssa Reductase antibodyAnti-AKR7A2 antibodyAnti-AFAR antibodyAnti-AFAR1 antibodyAnti-AKR7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
