Anti-AKAP7 antibody (STJA0007294)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human AKAP7
General Information
| Short Description | Rabbit polyclonal anti-A-kinase anchor protein 7 isoforms alpha and beta for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AKAP7 |
| Gene ID | 9465 |
| Uniprot ID | AKA7A_HUMAN |
| Immunogen | Synthesized peptide derived from human AKAP7 |
| Specificity | This antibody detects endogenous levels of AKAP7 at Human |
Additional Info
| Function | Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. |
| Protein Name | A-Kinase Anchor Protein 7 Isoforms Alpha And BetaAkap-7 Isoforms Alpha And BetaA-Kinase Anchor Protein 18 KdaAkap 18Protein Kinase A-Anchoring Protein 7 Isoforms Alpha/BetaPrka7 Isoforms Alpha/Beta |
| Database Links | |
| Cellular Localisation | Isoform Alpha: Lateral Cell MembraneLipid-AnchorTargeted Predominantly To The Lateral MembraneIsoform Beta: Apical Cell MembraneTargeted Predominantly To The Apical Membrane |
| Alternative Antibody Names | Anti-A-Kinase Anchor Protein 7 Isoforms Alpha And Beta antibodyAnti-Akap-7 Isoforms Alpha And Beta antibodyAnti-A-Kinase Anchor Protein 18 Kda antibodyAnti-Akap 18 antibodyAnti-Protein Kinase A-Anchoring Protein 7 Isoforms Alpha/Beta antibodyAnti-Prka7 Isoforms Alpha/Beta antibodyAnti-AKAP7 antibodyAnti-AKAP15 antibodyAnti-AKAP18 antibody |
Information sourced from Uniprot.org