| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-A-kinase anchor protein 7 isoforms alpha and beta is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AKAP7 |
| Gene ID: |
9465 |
| Uniprot ID: |
AKA7A_HUMAN |
| Specificity: |
This antibody detects endogenous levels of AKAP7 at Human |
| Immunogen: |
Synthesized peptide derived from human AKAP7 |
| Function | Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. |
| Protein Name | A-Kinase Anchor Protein 7 Isoforms Alpha And BetaAkap-7 Isoforms Alpha And BetaA-Kinase Anchor Protein 18 KdaAkap 18Protein Kinase A-Anchoring Protein 7 Isoforms Alpha/BetaPrka7 Isoforms Alpha/Beta |
| Cellular Localisation | Isoform Alpha: Lateral Cell MembraneLipid-AnchorTargeted Predominantly To The Lateral MembraneIsoform Beta: Apical Cell MembraneTargeted Predominantly To The Apical Membrane |
| Alternative Antibody Names | Anti-A-Kinase Anchor Protein 7 Isoforms Alpha And Beta antibodyAnti-Akap-7 Isoforms Alpha And Beta antibodyAnti-A-Kinase Anchor Protein 18 Kda antibodyAnti-Akap 18 antibodyAnti-Protein Kinase A-Anchoring Protein 7 Isoforms Alpha/Beta antibodyAnti-Prka7 Isoforms Alpha/Beta antibodyAnti-AKAP7 antibodyAnti-AKAP15 antibodyAnti-AKAP18 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
