| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-A-kinase anchor protein 7 isoforms alpha and beta is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AKAP7 |
| Gene ID: | 9465 |
| Uniprot ID: | AKA7A_HUMAN |
| Specificity: | This antibody detects endogenous levels of AKAP7 at Human |
| Immunogen: | Synthesized peptide derived from human AKAP7 |
| Function | Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. |
| Protein Name | A-Kinase Anchor Protein 7 Isoforms Alpha And Beta Akap-7 Isoforms Alpha And Beta A-Kinase Anchor Protein 18 Kda Akap 18 Protein Kinase A-Anchoring Protein 7 Isoforms Alpha/Beta Prka7 Isoforms Alpha/Beta |
| Cellular Localisation | Isoform Alpha: Lateral Cell Membrane Lipid-Anchor Targeted Predominantly To The Lateral Membrane Isoform Beta: Apical Cell Membrane Targeted Predominantly To The Apical Membrane |
| Alternative Antibody Names | Anti-A-Kinase Anchor Protein 7 Isoforms Alpha And Beta antibody Anti-Akap-7 Isoforms Alpha And Beta antibody Anti-A-Kinase Anchor Protein 18 Kda antibody Anti-Akap 18 antibody Anti-Protein Kinase A-Anchoring Protein 7 Isoforms Alpha/Beta antibody Anti-Prka7 Isoforms Alpha/Beta antibody Anti-AKAP7 antibody Anti-AKAP15 antibody Anti-AKAP18 antibody |
Information sourced from Uniprot.org