Anti-AHSG antibody (19-300) (STJ22552)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal AHSG (19-300) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AHSG |
| Gene ID | 197 |
| Uniprot ID | FETUA_HUMAN |
| Immunogen Region | 19-300 |
| Immunogen Sequence | APHGPGLIYRQPNCDDPETE EAALVAIDYINQNLPWGYKH TLNQIDEVKVWPQQPSGELF EIEIDTLETTCHVLDPTPVA RCSVRQLKEHAVEGDCDFQL LKLDGKFSVVYAKCDSSPDS AEDVRKVCQDCPLLAPLNDT RVVHAAKAALAAFNAQNNGS NFQLEEISRAQLVPLPPSTY VEFTVSGTDCVAKEATEAAK CNLLAEKQYGFCKATLSEKL GGAEVAVTCMVFQTQPVSS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 19-300 of human Fetuin A/Fetuin A/AHSG (NP_001613.2). |
Additional Info
| Tissue Specificity | Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. |
| Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. O- and N-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. N-glycan at Asn-156: Hex5HexNAc4.N-glycan heterogeneity at Asn-176: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor). |
| Function | Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. |
| Protein Name | Alpha-2-Hs-GlycoproteinAlpha-2-Z-GlobulinBa-Alpha-2-GlycoproteinFetuin-A Cleaved Into - Alpha-2-Hs-Glycoprotein Chain A - Alpha-2-Hs-Glycoprotein Chain B |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-6798695Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Alpha-2-Hs-Glycoprotein antibodyAnti-Alpha-2-Z-Globulin antibodyAnti-Ba-Alpha-2-Glycoprotein antibodyAnti-Fetuin-A Cleaved Into - Alpha-2-Hs-Glycoprotein Chain A - Alpha-2-Hs-Glycoprotein Chain B antibodyAnti-AHSG antibodyAnti-FETUA antibodyAnti-PRO2743 antibody |
Information sourced from Uniprot.org