| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AHSG (19-300) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AHSG |
| Gene ID: |
197 |
| Uniprot ID: |
FETUA_HUMAN |
| Immunogen Region: |
19-300 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 19-300 of human Fetuin A/Fetuin A/AHSG (NP_001613.2). |
| Immunogen Sequence: |
APHGPGLIYRQPNCDDPETE EAALVAIDYINQNLPWGYKH TLNQIDEVKVWPQQPSGELF EIEIDTLETTCHVLDPTPVA RCSVRQLKEHAVEGDCDFQL LKLDGKFSVVYAKCDSSPDS AEDVRKVCQDCPLLAPLNDT RVVHAAKAALAAFNAQNNGS NFQLEEISRAQLVPLPPSTY VEFTVSGTDCVAKEATEAAK CNLLAEKQYGFCKATLSEKL GGAEVAVTCMVFQTQPVSS |
| Tissue Specificity | Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. |
| Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. O- and N-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. N-glycan at Asn-156: Hex5HexNAc4.N-glycan heterogeneity at Asn-176: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor). |
| Function | Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. |
| Protein Name | Alpha-2-Hs-GlycoproteinAlpha-2-Z-GlobulinBa-Alpha-2-GlycoproteinFetuin-A Cleaved Into - Alpha-2-Hs-Glycoprotein Chain A - Alpha-2-Hs-Glycoprotein Chain B |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-6798695Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Alpha-2-Hs-Glycoprotein antibodyAnti-Alpha-2-Z-Globulin antibodyAnti-Ba-Alpha-2-Glycoprotein antibodyAnti-Fetuin-A Cleaved Into - Alpha-2-Hs-Glycoprotein Chain A - Alpha-2-Hs-Glycoprotein Chain B antibodyAnti-AHSG antibodyAnti-FETUA antibodyAnti-PRO2743 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
