Anti-ADRB1 antibody [6B9] (STJA0027715)

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STJA0027715
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Covered by St John's Laboratory Guarantee

Host: Human
Applications: ELISA/FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Human monoclonal antibody anti-Beta-1 Adrenergic Receptor is suitable for use in ELISA and Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : 6B9
Conjugation: Unconjugated
Isotype: VHH-hFc
Formulation: 9mM Citric acid monohydrate, 41mM Na2HPO4, 1% Mannitol, 5% Trehalose, 0.02% Tween 20, pH 6.5.
Purification: Protein A/G purified from cell culture supernatant.
Concentration: 2.22 mg/ml
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: ADRB1
Gene ID: 153
Uniprot ID: ADRB1_HUMAN
Function Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Involved in the regulation of sleep/wake behaviors.
Protein Name Beta-1 Adrenergic Receptor
Beta-1 Adrenoreceptor
Beta-1 Adrenoceptor
Database Links Reactome: R-HSA-390696
Reactome: R-HSA-418555
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Early Endosome
Colocalizes With Rapgef2 At The Plasma Membrane
Localized At The Plasma Membrane
Found In The Golgi Upon Gopc Overexpression
Alternative Antibody Names Anti-Beta-1 Adrenergic Receptor antibody
Anti-Beta-1 Adrenoreceptor antibody
Anti-Beta-1 Adrenoceptor antibody
Anti-ADRB1 antibody
Anti-ADRB1R antibody
Anti-B1AR antibody

Information sourced from Uniprot.org

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