Anti-ADRB1 antibody [6B9] (STJA0027715)
SPECIFICATIONS
ClonalityMonoclonal
HostHuman
ConjugationUnconjugated
IsotypeVHH-hFc
General Information
| Short Description | Human monoclonal Beta-1 Adrenergic Receptor antibody for use in ELISA and FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/FC |
| Host | Human |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 6B9 |
| Isotype | VHH-hFc |
| Conjugation | Unconjugated |
| Concentration | 2.22 mg/ml |
| Purification | Protein A/G purified from cell culture supernatant. |
| Formulation | 9mM Citric acid monohydrate, 41mM Na2HPO4, 1% Mannitol, 5% Trehalose, 0.02% Tween 20, pH 6.5. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | ADRB1 |
| Gene ID | 153 |
| Uniprot ID | ADRB1_HUMAN |
Additional Info
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Involved in the regulation of sleep/wake behaviors. |
| Protein Name | Beta-1 Adrenergic ReceptorBeta-1 AdrenoreceptorBeta-1 Adrenoceptor |
| Database Links | Reactome: R-HSA-390696Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinEarly EndosomeColocalizes With Rapgef2 At The Plasma MembraneLocalized At The Plasma MembraneFound In The Golgi Upon Gopc Overexpression |
| Alternative Antibody Names | Anti-Beta-1 Adrenergic Receptor antibodyAnti-Beta-1 Adrenoreceptor antibodyAnti-Beta-1 Adrenoceptor antibodyAnti-ADRB1 antibodyAnti-ADRB1R antibodyAnti-B1AR antibody |
Information sourced from Uniprot.org