| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADH1B |
| Gene ID: | 125 |
| Uniprot ID: | ADH1B_HUMAN |
| Immunogen Region: | 206-375 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 206-375 of human ADH1B (NP_000659.2). |
| Immunogen Sequence: | LSAVMGCKAAGAARIIAVDI NKDKFAKAKELGATECINPQ DYKKPIQEVLKEMTDGGVDF SFEVIGRLDTMMASLLCCHE ACGTSVIVGVPPASQNLSIN PMLLLTGRTWKGAVYGGFKS KEGIPKLVADFMAKKFSLDA LITHVLPFEKINEGFDLLHS GKSIRTVLTF |
| Function | Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate in retinoid metabolism. In vitro can also catalyze the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. |
| Protein Name | All-Trans-Retinol Dehydrogenase Nad(+ Adh1bAlcohol Dehydrogenase 1bAlcohol Dehydrogenase Subunit Beta |
| Database Links | Reactome: R-HSA-71384 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-All-Trans-Retinol Dehydrogenase Nad(+ Adh1b antibodyAnti-Alcohol Dehydrogenase 1b antibodyAnti-Alcohol Dehydrogenase Subunit Beta antibodyAnti-ADH1B antibodyAnti-ADH2 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and PRMT6 knockout (KO) 293T cells, using [KO Validated] PRMT6 Rabbit polyclonal antibody (STJ110124) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/88451/355635/STJ110124_1__38401.1713116745.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and PRMT6 knockout (KO) 293T cells, using [KO Validated] PRMT6 Rabbit polyclonal antibody (STJ110124) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.")
