Anti-ADH1B antibody (206-375) (STJ22517)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ADH1B (206-375) antibody for use in WB and ELISA in rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADH1B |
| Gene ID | 125 |
| Uniprot ID | ADH1B_HUMAN |
| Immunogen Region | 206-375 |
| Immunogen Sequence | LSAVMGCKAAGAARIIAVDI NKDKFAKAKELGATECINPQ DYKKPIQEVLKEMTDGGVDF SFEVIGRLDTMMASLLCCHE ACGTSVIVGVPPASQNLSIN PMLLLTGRTWKGAVYGGFKS KEGIPKLVADFMAKKFSLDA LITHVLPFEKINEGFDLLHS GKSIRTVLTF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 206-375 of human ADH1B (NP_000659.2). |
Additional Info
| Function | Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate in retinoid metabolism. In vitro can also catalyze the NADH-dependent reduction of all-trans-retinal and its derivatives such as all-trans-4-oxoretinal. Catalyzes in the oxidative direction with higher efficiency. Has the same affinity for all-trans-4-hydroxyretinol and all-trans-4-oxoretinal. |
| Protein Name | All-Trans-Retinol Dehydrogenase Nad(+ Adh1bAlcohol Dehydrogenase 1bAlcohol Dehydrogenase Subunit Beta |
| Database Links | Reactome: R-HSA-71384 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-All-Trans-Retinol Dehydrogenase Nad(+ Adh1b antibodyAnti-Alcohol Dehydrogenase 1b antibodyAnti-Alcohol Dehydrogenase Subunit Beta antibodyAnti-ADH1B antibodyAnti-ADH2 antibody |
Information sourced from Uniprot.org