| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Adgre1 (367-931) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Adgre1 |
| Gene ID: |
13733 |
| Uniprot ID: |
AGRE1_MOUSE |
| Immunogen Region: |
367-931 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 367-931 of mouse F4/80 (NP_034260.1). |
| Immunogen Sequence: |
KRILFKCKEDLILQSEQIQQ CQAVQGRDLGYASFCTLVNA TFTILDNTCENKSAPVSLQS AATSVSLVLEQATTWFELSK EETSTLGTILLETVESTMLA ALLIPSGNASQMIQTEYLDI ESKVINEECKENESINLAAR GDKMNVGCFIIKESVSTGAP GVAFVSFAHMESVLNERFFE DGQSFRKLRMNSRVVGGTVT GEKKEDFSKPIIYTLQHIQP KQKSERPICVSWNTDVEDG |
| Tissue Specificity | In macrophages.but absent from those which are localized within T-cell areas of lymph nodes and spleen. Low level of expression on blood monocytes. |
| Function | Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development. |
| Protein Name | Adhesion G Protein-Coupled Receptor E1Cell Surface Glycoprotein F4/80Egf-Like Module Receptor 1Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 1Emr1 Hormone Receptor |
| Database Links | Reactome: R-MMU-373080 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor E1 antibodyAnti-Cell Surface Glycoprotein F4/80 antibodyAnti-Egf-Like Module Receptor 1 antibodyAnti-Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 1 antibodyAnti-Emr1 Hormone Receptor antibodyAnti-Adgre1 antibodyAnti-Emr1 antibodyAnti-Gpf480 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Mouse abdominal macrophages elicited by starch broth were stained with Anti-F4/80 antibody (STJA0000122) [Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained macrophages (blank black histogram) were used as control.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/144975/291644/STJA0000122_1__19470.1631205427.jpg?c=1 "Mouse abdominal macrophages elicited by starch broth were stained with Anti-F4/80 antibody (STJA0000122) [Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained macrophages (blank black histogram) were used as control.")
