Anti-ADD2 antibody (471-520 aa) (STJ91491)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ADD2 at the amino acid range 471-520
STJ91491
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General Information

Short DescriptionRabbit polyclonal anti-Beta-adducin (471-520 aa) for use in WB, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IF/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:5000
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolADD2
Gene ID119
Uniprot IDADDB_HUMAN
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ADD2 at the amino acid range 471-520
Immunogen Region471-520 aa
SpecificityAdducin Beta Polyclonal Antibody detects endogenous levels of Adducin Beta protein.

Additional Info

Post Translational Modifications The N-terminus is blocked.
Function Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit.
Protein Name Beta-Adducin
Erythrocyte Adducin Subunit Beta
Database Links Reactome: R-HSA-5223345
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Alternative Antibody Names Anti-Beta-Adducin antibody
Anti-Erythrocyte Adducin Subunit Beta antibody
Anti-ADD2 antibody
Anti-ADDB antibody

Information sourced from Uniprot.org

Citations

Product Review