| Short Description : | Rabbit polyclonal anti-Beta-adducin (471-520 aa) for use in WB, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:5000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADD2 |
| Gene ID: | 119 |
| Uniprot ID: | ADDB_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ADD2 at the amino acid range 471-520 |
| Immunogen Region: | 471-520 aa |
| Specificity: | Adducin Beta Polyclonal Antibody detects endogenous levels of Adducin Beta protein. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit. |
| Protein Name | Beta-AdducinErythrocyte Adducin Subunit Beta |
| Database Links | Reactome: R-HSA-5223345 |
| Cellular Localisation | CytoplasmCytoskeletonCell MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Beta-Adducin antibodyAnti-Erythrocyte Adducin Subunit Beta antibodyAnti-ADD2 antibodyAnti-ADDB antibody |
Information sourced from Uniprot.org
