| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ADAMTSL1 (1483-1762) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ADAMTSL1 |
| Gene ID: |
92949 |
| Uniprot ID: |
ATL1_HUMAN |
| Immunogen Region: |
1483-1762 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1483-1762 of human ADAMTSL1 (NP_001035362.3). |
| Immunogen Sequence: |
SLVIQDYWWSVDRLATCSAS CGNRGVQQPRLRCLLNSTEV NPAHCAGKVRPAVQPIACNR RDCPSRWMVTSWSACTRSCG GGVQTRRVTCQKLKASGIST PVSNDMCTQVAKRPVDTQAC NQQLCVEWAFSSWGQCNGPC IGPHLAVQHRQVFCQTRDGI TLPSEQCSALPRPVSTQNCW SEACSVHWRVSLWTLCTATC GNYGFQSRRVECVHARTNKA VPEHLCSWGPRPANWQRCN |
| Tissue Specificity | Expressed primarily in adult skeletal muscle. |
| Post Translational Modifications | C-, N- and O-glycosylated. O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X(2)-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTSL1. Can also be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate secretion. Disulfide bonds are present. |
| Protein Name | Adamts-Like Protein 1Adamtsl-1Punctin-1 |
| Database Links | Reactome: R-HSA-5083635Reactome: R-HSA-5173214 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Adamts-Like Protein 1 antibodyAnti-Adamtsl-1 antibodyAnti-Punctin-1 antibodyAnti-ADAMTSL1 antibodyAnti-ADAMTSR1 antibodyAnti-C9orf94 antibodyAnti-UNQ528 antibodyAnti-PRO1071 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
