Anti-ACSL1 antibody [SRM14877] (STJ11109607)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal ACSL1 antibody for use in WB, IF-P, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF-P/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM14877 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB, 1:4000-1:30000IF-P, 1:200-1:1000IHC-P, 1:800-1:8000ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACSL1 |
| Gene ID | 2180 |
| Uniprot ID | ACSL1_HUMAN |
| Immunogen | Synthetic peptide. This information is considered to be commercially sensitive. |
Additional Info
| Tissue Specificity | Highly expressed in liver, heart, skeletal muscle, kidney and erythroid cells, and to a lesser extent in brain, lung, placenta and pancreas. |
| Function | Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate. Preferentially activates arachidonate than epoxyeicosatrienoic acids (EETs) or hydroxyeicosatrienoic acids (HETEs). |
| Protein Name | Long-Chain-Fatty-Acid--Coa Ligase 1Acyl-Coa Synthetase 1Acs1Arachidonate--Coa LigaseLong-Chain Acyl-Coa Synthetase 1Lacs 1Long-Chain Acyl-Coa Synthetase 2Lacs 2Long-Chain Fatty Acid-Coa Ligase 2Palmitoyl-Coa Ligase 1Palmitoyl-Coa Ligase 2Phytanate--Coa Ligase |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-2046105Reactome: R-HSA-2046106Reactome: R-HSA-75876Reactome: R-HSA-9841922 |
| Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Type Iii Membrane ProteinPeroxisome MembraneMicrosome MembraneEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Long-Chain-Fatty-Acid--Coa Ligase 1 antibodyAnti-Acyl-Coa Synthetase 1 antibodyAnti-Acs1 antibodyAnti-Arachidonate--Coa Ligase antibodyAnti-Long-Chain Acyl-Coa Synthetase 1 antibodyAnti-Lacs 1 antibodyAnti-Long-Chain Acyl-Coa Synthetase 2 antibodyAnti-Lacs 2 antibodyAnti-Long-Chain Fatty Acid-Coa Ligase 2 antibodyAnti-Palmitoyl-Coa Ligase 1 antibodyAnti-Palmitoyl-Coa Ligase 2 antibodyAnti-Phytanate--Coa Ligase antibodyAnti-ACSL1 antibodyAnti-FACL1 antibodyAnti-FACL2 antibodyAnti-LACS antibodyAnti-LACS1 antibodyAnti-LACS2 antibody |
Information sourced from Uniprot.org