Anti-ACO2 antibody (501-780) (STJ22487)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ACO2 (501-780) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ACO2 |
| Gene ID | 50 |
| Uniprot ID | ACON_HUMAN |
| Immunogen Region | 501-780 |
| Immunogen Sequence | IAGTLKFNPETDYLTGTDGK KFRLEAPDADELPKGEFDPG QDTYQHPPKDSSGQHVDVSP TSQRLQLLEPFDKWDGKDLE DLQILIKVKGKCTTDHISAA GPWLKFRGHLDNISNNLLIG AINIENGKANSVRNAVTQEF GPVPDTARYYKKHGIRWVVI GDENYGEGSSREHAALEPRH LGGRAIITKSFARIHETNLK KQGLLPLTFADPADYNKIHP VDKLTIQGLKDFTPGKPLK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 501-780 of human Aconitase 2 (Aconitase 2 (ACO2) ) (NP_001089.1). |
Additional Info
| Post Translational Modifications | Forms covalent cross-links mediated by transglutaminase TGM2, between a glutamine and the epsilon-amino group of a lysine residue, forming homopolymers and heteropolymers. |
| Function | Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. |
| Protein Name | Aconitate Hydratase - MitochondrialAconitaseCitrate Hydro-Lyase |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-71403Reactome: R-HSA-9837999Reactome: R-HSA-9854311 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Aconitate Hydratase - Mitochondrial antibodyAnti-Aconitase antibodyAnti-Citrate Hydro-Lyase antibodyAnti-ACO2 antibody |
Information sourced from Uniprot.org