| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACO2 |
| Gene ID: | 50 |
| Uniprot ID: | ACON_HUMAN |
| Immunogen Region: | 501-780 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 501-780 of human Aconitase 2 (Aconitase 2 (ACO2) ) (NP_001089.1). |
| Immunogen Sequence: | IAGTLKFNPETDYLTGTDGK KFRLEAPDADELPKGEFDPG QDTYQHPPKDSSGQHVDVSP TSQRLQLLEPFDKWDGKDLE DLQILIKVKGKCTTDHISAA GPWLKFRGHLDNISNNLLIG AINIENGKANSVRNAVTQEF GPVPDTARYYKKHGIRWVVI GDENYGEGSSREHAALEPRH LGGRAIITKSFARIHETNLK KQGLLPLTFADPADYNKIHP VDKLTIQGLKDFTPGKPLK |
| Post Translational Modifications | Forms covalent cross-links mediated by transglutaminase TGM2, between a glutamine and the epsilon-amino group of a lysine residue, forming homopolymers and heteropolymers. |
| Function | Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. |
| Protein Name | Aconitate Hydratase - Mitochondrial Aconitase Citrate Hydro-Lyase |
| Database Links | Reactome: R-HSA-1268020 Reactome: R-HSA-71403 Reactome: R-HSA-9837999 Reactome: R-HSA-9854311 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Aconitate Hydratase - Mitochondrial antibody Anti-Aconitase antibody Anti-Citrate Hydro-Lyase antibody Anti-ACO2 antibody |
Information sourced from Uniprot.org