| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-ABCF1 (746-845) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S7MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ABCF1 |
| Gene ID: |
23 |
| Uniprot ID: |
ABCF1_HUMAN |
| Immunogen Region: |
746-845 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 746-845 of human ABCF1 (Q8NE71). |
| Immunogen Sequence: |
GQKARVVFAELACREPDVLI LDEPTNNLDIESIDALGEAI NEYKGAVIVVSHDARLITET NCQLWVVEEQSVSQIDGDFE DYKREVLEALGEVMVSRPRE |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2 inhibits association of EIF2 with ribosomes. |
| Function | Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis. |
| Protein Name | Atp-Binding Cassette Sub-Family F Member 1Atp-Binding Cassette 50Tnf-Alpha-Stimulated Abc Protein |
| Database Links | Reactome: R-HSA-382556 |
| Cellular Localisation | Isoform 2: CytoplasmNucleusNucleoplasmNucleus Envelope |
| Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family F Member 1 antibodyAnti-Atp-Binding Cassette 50 antibodyAnti-Tnf-Alpha-Stimulated Abc Protein antibodyAnti-ABCF1 antibodyAnti-ABC50 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
