| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/FC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-ABCB5 (Internal) is suitable for use in ELISA, Western Blot and Flow Cytometry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.3-1µg/mlFC-Flow cytometric analysis of HepG2 cells. 10ug/mlELISA-antibody detection limit dilution 1:32000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
ABCB5 |
| Gene ID: |
340273 |
| Uniprot ID: |
ABCB5_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_848654.3; NP_001157413.1 |
| Specificity: |
This antibody is expected to recognise both reported isoforms (NP_848654.3; NP_001157413.1) |
| Immunogen Sequence: |
QTQHRNTSKKAQ |
| Function | Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair. |
| Protein Name | Atp-Binding Cassette Sub-Family B Member 5Abcb5 P-GpP-Glycoprotein Abcb5 |
| Database Links | Reactome: R-HSA-382556 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family B Member 5 antibodyAnti-Abcb5 P-Gp antibodyAnti-P-Glycoprotein Abcb5 antibodyAnti-ABCB5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
