Anti-5T4 antibody [DM137] (STJA0038108)

SKU:
STJA0038108-100
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Short Description :Rabbit monoclonal anti-5T4 for use in FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:FC/ELISA
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :DM137
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Chromatography
Dilution Range:FC 1:50-1:100
ELISA 1:10000
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:TPBG
Gene ID:7162
Uniprot ID:TPBG_HUMAN
Immunogen:Recombinant human 5T4 protein
Tissue Specificity Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.
Post Translational Modifications Highly glycosylated.
Function May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.
Protein Name Trophoblast Glycoprotein
5t4 Oncofetal Antigen
5t4 Oncofetal Trophoblast Glycoprotein
5t4 Oncotrophoblast Glycoprotein
M6p1
Wnt-Activated Inhibitory Factor 1
Waif1
Database Links
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Trophoblast Glycoprotein antibody
Anti-5t4 Oncofetal Antigen antibody
Anti-5t4 Oncofetal Trophoblast Glycoprotein antibody
Anti-5t4 Oncotrophoblast Glycoprotein antibody
Anti-M6p1 antibody
Anti-Wnt-Activated Inhibitory Factor 1 antibody
Anti-Waif1 antibody
Anti-TPBG antibody
Anti-5T4 antibody

Information sourced from Uniprot.org