Anti-5T4 antibody [DM137] (STJA0038108)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant human 5T4 protein
General Information
| Short Description | Rabbit monoclonal anti-5T4 for use in FC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | DM137 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | FC 1:50-1:100ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TPBG |
| Gene ID | 7162 |
| Uniprot ID | TPBG_HUMAN |
| Immunogen | Recombinant human 5T4 protein |
Additional Info
| Tissue Specificity | Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma. |
| Post Translational Modifications | Highly glycosylated. |
| Function | May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. |
| Protein Name | Trophoblast Glycoprotein5t4 Oncofetal Antigen5t4 Oncofetal Trophoblast Glycoprotein5t4 Oncotrophoblast GlycoproteinM6p1Wnt-Activated Inhibitory Factor 1Waif1 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Trophoblast Glycoprotein antibodyAnti-5t4 Oncofetal Antigen antibodyAnti-5t4 Oncofetal Trophoblast Glycoprotein antibodyAnti-5t4 Oncotrophoblast Glycoprotein antibodyAnti-M6p1 antibodyAnti-Wnt-Activated Inhibitory Factor 1 antibodyAnti-Waif1 antibodyAnti-TPBG antibodyAnti-5T4 antibody |
Information sourced from Uniprot.org