TGM1 Blocking Peptide for STJ503241 peptide (STJ504990)
SPECIFICATIONS
ImmunogenSynthetic peptide corresponding to unique amino acid sequence on Coagulation factor XIIIA chain precursor
General Information
| Short Description | TGM1 Blocking Peptide for STJ503241 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | F13a1 |
| Gene ID | 74145 |
| Uniprot ID | F13A_MOUSE |
| Immunogen | Synthetic peptide corresponding to unique amino acid sequence on Coagulation factor XIIIA chain precursor |
| Specificity | This blocking peptide is recommended for use in combination with TGM1 antibody, STJ503241 |
Additional Info
| Post Translational Modifications | The activation peptide is released by thrombin. |
| Function | Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. |
| Peptide Name | Coagulation Factor Xiii A ChainCoagulation Factor XiiiaProtein-Glutamine Gamma-Glutamyltransferase A ChainTransglutaminase A Chain |
| Database Links | Reactome: R-MMU-114608Reactome: -MMU-140875 |
| Cellular Localisation | CytoplasmSecretedSecreted Into The Blood PlasmaCytoplasmic In Most TissuesBut Also Secreted In The Blood Plasma |
| Alternative Peptide Names | Coagulation Factor Xiii A Chain proteinCoagulation Factor Xiiia proteinProtein-Glutamine Gamma-Glutamyltransferase A Chain proteinTransglutaminase A Chain proteinF13a1 proteinF13a protein |
Information sourced from Uniprot.org