| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
SYDE1 Positive Control for STJ503181 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
SYDE1 |
| Gene ID: |
85360 |
| Uniprot ID: |
SYDE1_HUMAN |
| Specificity: |
This is positive control is recommended for use in combination with SYDE1 antibody STJ503181. |
| Tissue Specificity | Expressed in trophoblast cells of placental villi. |
| Post Translational Modifications | Palmitoylated. Probably palmitoylated by ZDHHC3 and ZDHHC7. |
| Function | GTPase activator for the Rho-type GTPases. As a GCM1 downstream effector, it is involved in placental development and positively regulates trophoblast cells migration. It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1. |
| Peptide Name | Rho Gtpase-Activating Protein Syde1Synapse Defective Protein 1 Homolog 1Protein Syd-1 Homolog 1 |
| Database Links | Reactome: R-HSA-9013148Reactome: R-HSA-9013404Reactome: R-HSA-9013406Reactome: R-HSA-9013409Reactome: R-HSA-9013423Reactome: R-HSA-9035034 |
| Alternative Peptide Names | Rho Gtpase-Activating Protein Syde1 proteinSynapse Defective Protein 1 Homolog 1 proteinProtein Syd-1 Homolog 1 proteinSYDE1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
