| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | SUR1 Positive Control for STJ503162 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: | WB: 1:500 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Abcc8 |
| Gene ID: | 25559 |
| Uniprot ID: | ABCC8_RAT |
| Specificity: | This is positive control is recommended for use in combination with SUR1 antibody STJ503162. |
| Function | Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release. |
| Peptide Name | Atp-Binding Cassette Sub-Family C Member 8Sulfonylurea Receptor 1 |
| Database Links | Reactome: R-RNO-1296025Reactome: -RNO-422356 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Atp-Binding Cassette Sub-Family C Member 8 proteinSulfonylurea Receptor 1 proteinAbcc8 proteinSur proteinSur1 protein |
Information sourced from Uniprot.org