SLC26A3 Blocking Peptide for STJ506235 peptide (STJ505913)
SPECIFICATIONS
ImmunogenSynthetic peptide corresponding to amino acids within region 650-700 on human SCL26A3 protein.
General Information
| Short Description | SLC26A3 Blocking Peptide for STJ506235 is synthetically produced from the 650-700 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC26A3 |
| Gene ID | 1811 |
| Uniprot ID | S26A3_HUMAN |
| Immunogen | Synthetic peptide corresponding to amino acids within region 650-700 on human SCL26A3 protein. |
| Immunogen Region | 650-700 |
| Specificity | This blocking peptide is recommended for use in combination with SLC26A3 antibody, STJ506235 |
Additional Info
| Tissue Specificity | Expressed in the colon. Expression is significantly decreased in adenomas (polyps) and adenocarcinomas of the colon. |
| Post Translational Modifications | N-glycosylation is required for efficient cell surface expression, and protection from proteolytic degradation. |
| Function | Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. |
| Peptide Name | Chloride Anion ExchangerDown-Regulated In AdenomaProtein DraSolute Carrier Family 26 Member 3 |
| Database Links | Reactome: R-HSA-427601Reactome: R-HSA-5619085 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinMembraneCell MembraneLocalized In Sperm MembranesMidpiece Of Sperm TailColocalizes With Cftr At The Midpiece Of Sperm Tail |
| Alternative Peptide Names | Chloride Anion Exchanger proteinDown-Regulated In Adenoma proteinProtein Dra proteinSolute Carrier Family 26 Member 3 proteinSLC26A3 proteinDRA protein |
Information sourced from Uniprot.org