Applications: |
WB |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
SFRP5 Positive Control for STJ502967 is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Dilution Range: |
WB: 1:500 |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
SFRP5 |
Gene ID: |
6425 |
Uniprot ID: |
SFRP5_HUMAN |
Specificity: |
This is positive control is recommended for use in combination with SFRP5 antibody STJ502967. |
Tissue Specificity | Highly expressed in the retinal pigment epithelium (RPE) and pancreas. Weak expression in heart, liver and muscle. |
Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina. |
Peptide Name | Secreted Frizzled-Related Protein 5Sfrp-5Frizzled-Related Protein 1bFrp-1bSecreted Apoptosis-Related Protein 3Sarp-3 |
Cellular Localisation | Secreted |
Alternative Peptide Names | Secreted Frizzled-Related Protein 5 proteinSfrp-5 proteinFrizzled-Related Protein 1b proteinFrp-1b proteinSecreted Apoptosis-Related Protein 3 proteinSarp-3 proteinSFRP5 proteinFRP1B proteinSARP3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance