ROR2 Blocking Peptide for STJ502830 peptide (STJ504870)

SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid region 900-943 on human ROR2 protein.
STJ504870-250
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General Information

Short DescriptionROR2 Blocking Peptide for STJ502830 is synthetically produced from the 900-943 sequence and is suitable for use in western blot applications.
ApplicationsImmunodepletion/Immunocompetition
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

FormulationLiquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage InstructionStore at-20°C for long term storage. Avoid freeze-thaw cycles.

Target Information

Gene SymbolROR2
Gene ID4920
Uniprot IDROR2_HUMAN
ImmunogenSynthetic peptide taken within amino acid region 900-943 on human ROR2 protein.
Immunogen Region900-943
SpecificityThis blocking peptide is recommended for use in combination with ROR2 antibody, STJ502830

Additional Info

Function Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling.
Peptide Name Tyrosine-Protein Kinase Transmembrane Receptor Ror2
Neurotrophic Tyrosine Kinase - Receptor-Related 2
Database Links Reactome: R-HSA-4086400
Reactome: R-HSA-5140745
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Peptide Names Tyrosine-Protein Kinase Transmembrane Receptor Ror2 protein
Neurotrophic Tyrosine Kinase - Receptor-Related 2 protein
ROR2 protein
NTRKR2 protein

Information sourced from Uniprot.org

Citations

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