Applications: |
Immunodepletion/Immunocompetition |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
RNase H1 Blocking Peptide for STJ506221 is synthetically produced from the 1-75 sequence and is suitable for use in western blot applications. |
Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
RNASEH1 |
Gene ID: |
246243 |
Uniprot ID: |
RNH1_HUMAN |
Immunogen Region: |
1-75 |
Specificity: |
This blocking peptide is recommended for use in combination with RNase H1 antibody, STJ506221 |
Immunogen: |
Synthetic peptide corresponding to amino acids within region 1-75 on human Rnase H1 protein. |
Function | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II. |
Peptide Name | Ribonuclease H1Rnase H1Ribonuclease H Type Ii |
Cellular Localisation | Cytoplasm |
Alternative Peptide Names | Ribonuclease H1 proteinRnase H1 proteinRibonuclease H Type Ii proteinRNASEH1 proteinRNH1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance