Applications: | WB |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | RHBDF2 Positive Control for STJ506169 is synthetically produced from the 1-50 sequence and is suitable for use in western blot applications. |
Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | RHBDF2 |
Gene ID: | 79651 |
Uniprot ID: | RHDF2_HUMAN |
Immunogen Region: | 1-50 |
Specificity: | This is positive control is recommended for use in combination with RHBDF2 antibody STJ506169. |
Immunogen: | Synthetic peptide taken within amino aid region 1-50 on human Inactive rhomboid protein 2. |
Tissue Specificity | Found in the epidermis and esophageal epithelium. |
Function | Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own. |
Peptide Name | Inactive Rhomboid Protein 2 Irhom2 Rhomboid 5 Homolog 2 Rhomboid Family Member 2 Rhomboid Veinlet-Like Protein 5 Rhomboid Veinlet-Like Protein 6 |
Database Links | Reactome: R-HSA-9662834 |
Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein Cell Membrane |
Alternative Peptide Names | Inactive Rhomboid Protein 2 protein Irhom2 protein Rhomboid 5 Homolog 2 protein Rhomboid Family Member 2 protein Rhomboid Veinlet-Like Protein 5 protein Rhomboid Veinlet-Like Protein 6 protein RHBDF2 protein IRHOM2 protein RHBDL5 protein RHBDL6 protein |
Information sourced from Uniprot.org