RCE1 Blocking Peptide for STJ502759 peptide (STJ504848)
SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid sequence 300-350 on human RCE1 protein.
General Information
| Short Description | RCE1 Blocking Peptide for STJ502759 is synthetically produced from the 300-350 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | RCE1 |
| Gene ID | 9986 |
| Uniprot ID | FACE2_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid sequence 300-350 on human RCE1 protein. |
| Immunogen Region | 300-350 |
| Specificity | This blocking peptide is recommended for use in combination with RCE1 antibody, STJ502759 |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Ubiquitinated. Undergoes 'Lys-48'- and 'Lys-63'-linked ubiquitination. 'Lys-48' ubiquitination induces its degradation. Deubiquitinated by USP17L2/USP17 that cleaves 'Lys-63'-linked ubiquitin chains. |
| Function | Protease involved in the processing of a variety of prenylated proteins containing the C-terminal CAAX motif, where C is a cysteine modified with an isoprenoid lipid, A is an aliphatic amino acid and X is any C-terminal amino acid. Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins, leaving the prenylated cysteine as the new C-terminus. Is able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1. |
| Peptide Name | Caax Prenyl Protease 2Farnesylated Proteins-Converting Enzyme 2Face-2Prenyl Protein-Specific Endoprotease 2Rce1 HomologHrce1 |
| Database Links | Reactome: R-HSA-5689880Reactome: R-HSA-9648002 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Caax Prenyl Protease 2 proteinFarnesylated Proteins-Converting Enzyme 2 proteinFace-2 proteinPrenyl Protein-Specific Endoprotease 2 proteinRce1 Homolog proteinHrce1 proteinRCE1 proteinFACE2 proteinRCE1A proteinRCE1B protein |
Information sourced from Uniprot.org