Rat PTGES (Prostaglandin E Synthase, Microsomal) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018117)
SPECIFICATIONS
General Information
| Short Description | This PTGES Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Rat |
| Sensitivity | 0.068ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | Ptges |
| Gene ID | 59103 |
| Uniprot ID | PTGES_RAT |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Terminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inflammatory stimuli. Plays a key role in inflammation response, fever and pain. Also catalyzes the oxidoreduction of endocannabinoids into prostaglandin glycerol esters and PGG2 into 15-hydroperoxy-PGE2. In addition, displays low glutathione transferase and glutathione-dependent peroxidase activities, toward 1-chloro-2,4-dinitrobenzene and 5-hydroperoxyicosatetraenoic acid (5-HPETE), respectively. |
| Protein Name | Prostaglandin E SynthaseMpges-1Glutathione Peroxidase PtgesGlutathione Transferase PtgesInducible Prostaglandin E SynthaseMicrosomal Prostaglandin E Synthase 1 |
| Database Links | Reactome: R-RNO-2162123 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCytoplasmPerinuclear RegionColocalizes With Ptgs1/Cox-1 And Ptgs2/Cox-2 In The Perinuclear Compartment |
| Alternative ELISA Names | Prostaglandin E Synthase ELISA kitMpges-1 ELISA kitGlutathione Peroxidase Ptges ELISA kitGlutathione Transferase Ptges ELISA kitInducible Prostaglandin E Synthase ELISA kitMicrosomal Prostaglandin E Synthase 1 ELISA kitPtges ELISA kitPges ELISA kitPig12 ELISA kit |
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Information sourced from Uniprot.org