Rat OAS1 (2 NA, 5 Oligoadenylate Synthetase 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017538)
SPECIFICATIONS
General Information
| Short Description | This OAS1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Rat |
| Sensitivity | 0.25ng/mL |
| Detection Limit | 0.781-50ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | Oas1a |
| Gene ID | 192281 |
| Uniprot ID | OAS1A_RAT |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L. |
| Protein Name | 2'-5'-Oligoadenylate Synthase 1a(2-5'Oligo(A Synthase 1a2-5a Synthase 1a |
| Database Links | |
| Cellular Localisation | CytoplasmMitochondrionNucleusMicrosomeEndoplasmic ReticulumAssociated With Different Subcellular Fractions Such As MitochondrialNuclearAnd Rough/Smooth Microsomal Fractions |
| Alternative ELISA Names | 2'-5'-Oligoadenylate Synthase 1a ELISA kit(2-5'Oligo(A Synthase 1a ELISA kit2-5a Synthase 1a ELISA kitOas1a ELISA kitOas1 ELISA kit |
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Information sourced from Uniprot.org