| Tissue Specificity | Expressed in flagella of epididymal sperm. The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. |
| Post Translational Modifications | ISGylated. Lysine 2-hydroxyisobutyrylation (Khib) by p300/EP300 activates the phosphopyruvate hydratase activity. |
| Function | Glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. |
| Protein Name | Alpha-Enolase2-Phospho-D-Glycerate Hydro-LyaseEnolase 1Non-Neural EnolaseNne |
| Database Links | |
| Cellular Localisation | CytoplasmCell MembraneCan Translocate To The Plasma Membrane In Either The Homodimeric (Alpha/Alpha) Or Heterodimeric (Alpha/Gamma) Form |
| Alternative ELISA Names | Alpha-Enolase ELISA kit2-Phospho-D-Glycerate Hydro-Lyase ELISA kitEnolase 1 ELISA kitNon-Neural Enolase ELISA kitNne ELISA kitEno1 ELISA kitEno-1 ELISA kit |
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Information sourced from Uniprot.org
