Rat IL-1R1 (Interleukin-1 Receptor Type 1) Antibody Pair (STJAP00335)
General Information
| Short Description | This IL-1R1 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Rat |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Protein A & Antigen Affinity.Detection Purification: Protein A & Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Il1r1Uniprot ID=IL1R1_RAT" |
| Immunogen | Capture immunogen: Recombinant Rat IL-1R1 protein.Detection Immunogen: Recombinant Rat IL-1R1 protein. |
Additional Info
| Function | Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells. |
| Protein Name | Interleukin-1 Receptor Type 1Il-1r-1Il-1rt-1Il-1rt1Cd121 Antigen-Like Family Member AInterleukin-1 Receptor AlphaIl-1r-AlphaInterleukin-1 Receptor Type IP80Cd Antigen Cd121a Cleaved Into - Interleukin-1 Receptor Type 1 - Membrane FormMil-1r1Mil-1ri - Interleukin-1 Receptor Type 1 - Soluble FormSil-1r1Sil-1ri |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell MembraneSecreted |
| Alternative Antibody Pair Names | Interleukin-1 Receptor Type 1 antibody pairIl-1r-1 antibody pairIl-1rt-1 antibody pairIl-1rt1 antibody pairCd121 Antigen-Like Family Member A antibody pairInterleukin-1 Receptor Alpha antibody pairIl-1r-Alpha antibody pairInterleukin-1 Receptor Type I antibody pairP80 antibody pairCd Antigen Cd121a Cleaved Into - Interleukin-1 Receptor Type 1 - Membrane Form antibody pairMil-1r1 antibody pairMil-1ri - Interleukin-1 Receptor Type 1 - Soluble Form antibody pairSil-1r1 antibody pairSil-1ri antibody pairIl1r1 antibody pairIl1ra antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Rat IL-1R1 (Interleukin-1 Receptor Type 1) Antibody Pair (STJAP00335)
This antibody pair detects rat IL-1R1 (Interleukin-1 Receptor Type 1), corresponding to UniProt entry Q02955. Reactivity is confirmed for rat only.
Both antibodies are rabbit polyclonal, supplied at 0.5 mg/mL. The capture antibody is unconjugated, while the detection antibody is biotin-conjugated. Both are formulated in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.4.
This antibody pair is validated for ELISA. No other assay formats are specified for this product.
Both antibodies were raised against recombinant rat IL-1R1 protein. Both were purified by Protein A and antigen affinity methods.
Both components should be stored at -20°C for long-term storage. Repeated freeze-thaw cycles should be avoided.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.