Rat IL-1R1 (Interleukin-1 Receptor Type 1) Antibody Pair (STJAP00335)

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STJAP00335-50
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Host: Rabbit/Rabbit
Applications: ELISA
Reactivity: Rat
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : This IL-1R1 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
Clonality : Polyclonal/Polyclonal
Conjugation: Unconjugated/Biotin
Formulation: Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.
Purification: Capture Purification: Protein A & Antigen Affinity.
Detection Purification: Protein A & Antigen Affinity.
Concentration: 0.5 mg/mL
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: Il1r1
Uniprot ID: IL1R1_RAT
Immunogen: Capture immunogen: Recombinant Rat IL-1R1 protein.
Detection Immunogen: Recombinant Rat IL-1R1 protein.
Function Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells.
Protein Name Interleukin-1 Receptor Type 1
Il-1r-1
Il-1rt-1
Il-1rt1
Cd121 Antigen-Like Family Member A
Interleukin-1 Receptor Alpha
Il-1r-Alpha
Interleukin-1 Receptor Type I
P80
Cd Antigen Cd121a Cleaved Into - Interleukin-1 Receptor Type 1 - Membrane Form
Mil-1r1
Mil-1ri - Interleukin-1 Receptor Type 1 - Soluble Form
Sil-1r1
Sil-1ri
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Membrane
Secreted
Alternative Antibody Pair Names Interleukin-1 Receptor Type 1 antibody pair
Il-1r-1 antibody pair
Il-1rt-1 antibody pair
Il-1rt1 antibody pair
Cd121 Antigen-Like Family Member A antibody pair
Interleukin-1 Receptor Alpha antibody pair
Il-1r-Alpha antibody pair
Interleukin-1 Receptor Type I antibody pair
P80 antibody pair
Cd Antigen Cd121a Cleaved Into - Interleukin-1 Receptor Type 1 - Membrane Form antibody pair
Mil-1r1 antibody pair
Mil-1ri - Interleukin-1 Receptor Type 1 - Soluble Form antibody pair
Sil-1r1 antibody pair
Sil-1ri antibody pair
Il1r1 antibody pair
Il1ra antibody pair

Information sourced from Uniprot.org

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