Rat FAS/CD95 (Tumor Necrosis Factor Receptor Superfamily Member 6) Antibody Pair (STJAP00351)
General Information
| Short Description | This FAS/CD95 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Goat/Goat |
| Reactivity | Rat |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Fas |
| Gene ID | 246097 |
| Uniprot ID | TNR6_RAT |
| Immunogen | Capture immunogen: Recombinant Rat FAS/CD95 protein.Detection Immunogen: Recombinant Rat FAS/CD95 protein. |
Additional Info
| Function | Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 6Apo-1 AntigenApoptosis-Mediating Surface Antigen FasFaslg ReceptorCd Antigen Cd95 |
| Database Links | Reactome: R-RNO-3371378Reactome: -RNO-5218900Reactome: -RNO-69416Reactome: -RNO-75157 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinMembrane Raft |
| Alternative Antibody Pair Names | Tumor Necrosis Factor Receptor Superfamily Member 6 antibody pairApo-1 Antigen antibody pairApoptosis-Mediating Surface Antigen Fas antibody pairFaslg Receptor antibody pairCd Antigen Cd95 antibody pairFas antibody pairApt1 antibody pairTnfrsf6 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Rat FAS/CD95 (Tumor Necrosis Factor Receptor Superfamily Member 6) Antibody Pair (STJAP00351)
This antibody pair detects rat FAS/CD95 (Tumor Necrosis Factor Receptor Superfamily Member 6), corresponding to UniProt entry Q63199. Reactivity has been confirmed for rat only.
Both antibodies are polyclonal, raised in goat, and supplied at 0.5 mg/mL. The capture antibody is unconjugated, while the detection antibody is biotinylated. Both are formulated in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.4.
This antibody pair is validated for use in ELISA. No other assay formats are specified in the product documentation.
Both the capture and detection antibodies were raised against recombinant rat FAS/CD95 protein. Both antibodies were subsequently purified by antigen affinity chromatography.
Both components should be stored at -20°C for long-term storage. Freeze-thaw cycles should be avoided to maintain reagent integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.