Rat EAAT2 (Excitatory Amino Acid Transporter 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014931)
SPECIFICATIONS
General Information
| Short Description | This EAAT2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Rat |
| Sensitivity | 0.058ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | Slc1a2 |
| Gene ID | 29482 |
| Uniprot ID | EAA2_RAT |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Localized in brain and is highly enriched in the Purkinje cell layer in cerebellum. |
| Post Translational Modifications | Glycosylated. Palmitoylation at Cys-38 is not required for correct subcellular localization, but is important for glutamate uptake activity. |
| Function | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate. |
| Protein Name | Excitatory Amino Acid Transporter 2Glt-1Sodium-Dependent Glutamate/Aspartate Transporter 2Glut-RSolute Carrier Family 1 Member 2 |
| Database Links | Reactome: R-RNO-210455Reactome: -RNO-210500Reactome: -RNO-425393 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Excitatory Amino Acid Transporter 2 ELISA kitGlt-1 ELISA kitSodium-Dependent Glutamate/Aspartate Transporter 2 ELISA kitGlut-R ELISA kitSolute Carrier Family 1 Member 2 ELISA kitSlc1a2 ELISA kitEaat2 ELISA kitGlt1 ELISA kit |
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Information sourced from Uniprot.org